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Laboratory of Bioinformatics PDF Print E-mail

Laboratory of Bioinformatics

Dipartimento di Informatica e Sistemistica, Università di Pavia

via Ferrata 1, 27100 Pavia, Italy

 

The Laboratory of Bioinformatics aims at supporting genomic and clinical medicine by the application of the formal methods of Biomedical Informatics and Bioengineering. Our ultimate goal is to provide decision support methods and Information Technology solutions able to favour the discovery of new diagnostic and prognostic tools and new therapeutic method and to improve clinical decision making as well as scientific discovery processes. The Laboratory has strong expertise in developing advanced methods and tools for supporting molecular biology, molecular medicine, and translational research, with a specific focus on high-throughput experiments. In particular, the Laboratory is currently developing software solutions for data analysis workflow management, intelligent data querying and exploration, integrated search on biological data and knowledge repositories, text mining of scientific literature, and multi-level -omics networks analysis.

The research field is:

  • Bioinformatics for Tissue Engineering. Crucial to the interpretation of high-throughput experimental data is the integration of data analysis and biological knowledge. A proper bioinformatics approach is therefore essential to tissue engineering research to determine the choice of cellular lines, the scaffolds properties and the optimal environmental conditions for bioreactors. The main research area of the Laboratory will deal with a research topic which inherently requires computational biology and bioinformatics approaches: the study of the mechanisms underlying in vitro skeletal muscle tissue formation, aimed at developing transplantable artificial human tissues.